Tampa police say Mays' wife Deborah found him unresponsive at his Tampa-area home Sunday morning. Tampa Fire Rescue pronounced him deceased at 7:45 a.m.
The cause of death is unknown. Police say there were no signs of forced entry to the residence and there is no suspected foul play.
Mays was on the US Airways flight from Philadelphia that had a hard landing Saturday at Tampa International Airport after the front tire under the nose of the plane blew out.
After the flight, Tampa TV station quoted Mays as saying, "All of a sudden as we hit, you know, it was just the hardest hit, all the things from the ceiling started dropping. It hit me on the head, but I got a hard head."
Airline spokesman Jim Olson told CNN Sunday there were no reported passenger injuries from flight 1241. The airline vowed to "cooperate fully" with authorities in the investigation.
Billy Mays was about to film a bunch of commercials for Taco Bell -- this according to a radio host who talked to the pitchman a few hours before he died. During the call, Todd said Billy had just signed a deal with Taco Bell for a series of infomercial-style adverts that were going to be filmed in August.